Susan G. Komen is making metastatic breast cancer (MBC) a top priority for public policy, research and ongoing education and patient support programs.


We must understand the biology of breast cancer and metastasis to develop drugs to slow, stop and prevent it. Metastatic breast cancers, by and large, are more resistant to the standard therapies we have today. That’s why it’s going to take innovative research and breakthrough discoveries to detect, target and find the cures for this disease. Susan G. Komen has invested more than $210 million in MBC research, supporting more than 500 research grants, including more than 50 clinical trials.

education & information

MBC is the most advanced stage of breast cancer—also known as Stage IV. It causes nearly all of the more than 42,000 breast cancer deaths each year in the United States. If you are a caregiver, a loved one, recently diagnosed with breast cancer, or living with MBC, we provide breast cancer information that is safe, accurate, reliable and based on scientific evidence and presented in a variety of formats.


In the United States, it’s estimated that more than 168,000 women have MBC. We want everyone to benefit from the scientific discoveries that are improving treatment for MBC and have the information and support needed to face the unique challenges and concerns of living with MBC. Komen works with partners in thousands of communities to unlock the scientific discoveries and deliver the support needed to help people with MBC.


We need policymakers to understand and prioritize the needs of women and men impacted by breast cancer, especially those living with metastatic breast cancer. Komen is actively engaged in Washington, D.C. and capitals across the country to create broad, long-lasting changes that will expand research funding and increase access to high-quality, affordable care for all patient populations.


Clinical trials are key to making progress against MBC. Patients who join clinical trials receive high-quality care while contributing to the research process that could help themselves or others. Komen wants to help people with MBC find-and participate in-clinical trials.

Call our Clinical Trial Information Helpline to speak with a trained specialist.

1-877 GO KOMEN

or email at

Use the Metastic Trial Search Tool to find a Trial that’s Right for You.

Hear from Our Metastatic Breast Cancer Community

Real perspective, stories and advice from those living with MBC.

What is Metastatic Breast Cancer? Pam Kohl explains

Living with Metastatic Breast Cancer with Jamil Rivers

The Importance of Forgiveness, by Abigail Letts

mbc impact series

Upcoming Metastatic Breast Cancer Events

Komen’s Metastatic Breast Cancer (MBC) Impact Series will provide people living with MBC and their loved ones a safe, collaborative space to gather information and discover practical resources needed to make decisions for improved physical and emotional health. The series will begin in April and continue monthly through December 2021. During each month’s event, you will be able to participate in live sessions featuring leading experts in their fields, individuals living with MBC sharing their stories, and learn how to improve wellness.

To learn more and register for the series of events, click here.